We investigate alterations of chromosomal and genomic structures and functions as well as changes of chromatin architecture and activity in pancreatic cancer cell plasticity.
Utilizing sophisticated models of pancreatic cancer we aim at translating molecular findings in pancreatic cancer research to the clinic.
In this research focus we explore and modulate the complex communication between pancreatic cancer cells and their environment.
Herein we dissect cellular and molecular mechanisms of inflammation- and obesity-associated diseases.
Herein we focus on exploring changes of the microbiome in inflammatory and malignant pancreatic diseases.
This research consortium funded by the German Research foundation explores the role of subtype-driven genome dynamics for pancreatic cancer progression and therapy.